The canine alkaline phosphatases: a review of the isoenzymes in serum, analytical methods and their diagnostic application.
نویسندگان
چکیده
This paper reviews the alkaline phosphatases in canine serum, the analytical methods used for qualitative and/or quantitative detection of these isoenzymes, and the diagnostic significancy of each of these isoenzymes. The paper further describes some of the latest advances in our knowledge of the canine alkaline phosphatases and possible areas of future research.
منابع مشابه
P-178: Separation and Identification of Alkaline Phosphatase Isozymes during Pregnancy
Background: Alkaline phosphatase (ALP), (EC 3.1.3.1) is a hydrolase enzyme responsible for removing phosphate groups from various molecules in the body. In humans, ALPis present in all tissues such as liver, bile duct, kidney, bone, and the placenta which detection of its activity is so useful in molecular biology. Pregnancy is associated with normal physiological changes that assist fetal surv...
متن کاملSeparation and Characterization of Alkaline Phosphatase Isoenzymes from Blood and Other Tissues
Alkaline phosphatases may be contributed to the blood by a number of organs; thus the serum alkaline phosphatase may consist of a mixture of phosphatase isoenzymes. Whether or not these isoenzymes differ other than in their tissues of origin has long been debated, some evidence indicating that they are identical, some that they are different. Attempts to characterize alkaline phosphatase by a s...
متن کاملPurification and Characterization of Two Acid Phosphatases from Germinating Peanut (Arachis hypogaea) Seed
The maximum acid phosphatasic activity was detected in peanut seed at the 5th day of germination. At least, two acid phosphatases were purified by successive chromatography separations on DEAE-Sepharose CL-6B, CM-Sepharose CL-6B, Sephacryl S-100 HR, and Phenyl-Sepharose HP to apparent homogeneity from five days old cotyledon of peanut after germination. These isoenzymes, designated peanut cotyl...
متن کاملAlkaline Phosphatase lsoenzymes
The human alkaline phosphatases constitute a system of multiple molecular forms of enzymes in which heterogeneity is partly due to genetic factors and partly to posttranslational modifications. Recognition of the nature and occurrence of these multiple forms has made a significant contribution both to the understanding of changes in alkaline phosphatase values for serum in disease and to the us...
متن کاملThe effects of chromium and cadmium on the activity of alkaline phosphatase lsoenzmes in rats
The aim of this study was to Investigate the toxic effects of chromium and cadmium on the activity of two isoenzymes of alkaline phosphatase in vitro and in vivo experiments. Oral administration and peritoneal injection of CdCl2 or CrCl3 in rats reduced serum alkaline phosphatase by 21.5℅ and 25.5℅ respectively. At the same time high molecular weight alkaline phosphatase was elevated by 138℅ a...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
- The Japanese journal of veterinary research
دوره 46 1 شماره
صفحات -
تاریخ انتشار 1998